The fourth appointment with Alberto Angela's program begins with extraordinary images in the ice of northern Canada: "Noos - The adventure of knowledge", here a mother bear with her cubs begins a march in search of food to feed herself and her cubs. We will then go to Ravenna to visit one of the state-of-the-art pain therapy departments, then we will talk about food and nutrition, cruise holidays and, with Samantha Cristoforetti, about Mars. Archeology will not be missing, in fact we will see the great engineering works carried out in Ancient Rome, as well as guests, one of these Roberto Cingolani, historical face of "Superquark". There will be a part dedicated to the story with Carlo Lucarelli and we will also try to understand how to avoid wasting water. As always, experiments, curiosities, insights and much more!