Frate's betrayal has left Nero on the run with the Vanetti family in pursuit. To save the badly injured Tigre, Nero seeks the aid of Fango, who is currently holed up on the Island. In exchange for his help, Nero agrees to bring Don Orco to Fango alive. To that end, Avilio and Nero head for Orco's base of operations, Ottimo Orco.